Many potential patients for surgery are concerned to know about Bladder Cancer treatment cost In India? The Average cost of Bladder Cancer treatment In India usually starts $2000 however, it may go up to as much as $15000. It depends on the hospital charges and the fee charged by the surgeon. which includes initial investigations & specialists screening, stay in a room wherein the patient’s assistant or relative can also stay with the patient, Doctor/Surgeon fee, Nursing care, Medicines & Consumables, airport pick-up & drop.
Bladder cancer growth is a typical kind of disease that starts in the cells of the bladder. The bladder is an empty solid organ in your lower abdomen that stores urine.
Bladder cancer most often begins in the cells (urothelial cells) that line the within of your bladder. Urothelial cells are also found in your kidneys and the tubes (ureters) that connect the kidneys to the bladder. Urothelial cancer can occur in the kidneys and ureters, as well, yet it’s considerably more typical in the bladder.
Most bladder cancers are diagnosed at an early stage when the cancer is highly treatable. However, even beginning stage bladder diseases can return after successful treatment. For this reason, individuals with bladder cancer generally need follow-up tests for quite a long time after treatment to look for bladder cancer that recurs.
The type of bladder cancer depends on how the tumor’s cells look under the microscope. The 3 main types of bladder cancer are:
There are other, less common types of bladder cancer, including sarcoma of the bladder and small cell bladder cancer. Sarcomas of the bladder frequently start in the fat or muscle layers of the bladder. small cell bladder cancer is an uncommon sort of bladder cancer that is probably going to spread to different pieces of the body.
The main symptom of bladder cancer is blood in your urine. This is the same for both men and women.
It can also help if you tell them whether:
Other symptoms of bladder cancer can include:
These symptoms are much more likely to be caused by other conditions rather than cancer. For example, a urine infection, particularly if you do not have blood in your urine. For men, the symptoms could be caused by an enlarged prostate gland.
The commonest causes are smoking of cigarettes, bidis, hookah, and exposure to chemicals in industries such as dyes, metal, paints, leather, textile, and organic chemicals. More than 90 percent of all bladder cancers originate in the urothelium and then may invade the lamina propria and detrusor muscle.
Your doctor may diagnose bladder cancer using one or more of the following methods:
Your doctor can rate bladder cancer with a staging system that goes from stages 0 to 4 to identify how far cancer has spread. The stages of bladder cancer mean the following:
Stage 0 bladder cancer hasn’t spread past the lining of the bladder.
Stage 1 bladder cancer has spread past the lining of the bladder, but it hasn’t reached the layer of muscle in the bladder.
Stage 2 bladder cancer has spread to the layer of muscle in the bladder.
Stage 3 bladder cancer has spread into the tissues that surround the bladder.
Stage 4 bladder cancer has spread past the bladder to the neighboring areas of the body.
Your doctor will work with you to decide what is the best treatment to provide based on the type and stage of your bladder cancer, your symptoms, and your overall health.
Treatment for stage 0 and stage 1 bladder cancer might include surgery to remove the tumor from the bladder, chemotherapy, or immunotherapy, which involves taking a medication that causes your immune system to attack the cancer cells.
Treatment for stage 2 and stage 3 bladder cancer may include:
Treatment for stage 4 bladder cancer may include:
Basic descriptions of the most common types of treatments used for bladder cancer are listed below. Take time to learn about all of your treatment options and be sure to ask questions about things that are unclear. Also, talk about the goals and benefits of each treatment with your doctor and what you can expect while receiving the treatment. These types of talks are called “shared decision making.” Shared decision making is when you and your doctors work together to choose treatments that fit the goals of your care. Shared decision making is particularly important for bladder cancer because there are different treatment options.
To see general treatment options based on the extent of the bladder cancer, read the next section in this guide, Treatments by Stage.
Surgery is the removal of the tumor and some surrounding healthy tissue during an operation. There are different types of surgery for bladder cancer. Your health care team will recommend a specific surgery based on the stage and grade of the disease. Surgical options to treat bladder cancer include:
The side effects of bladder cancer surgery depend on the procedure. Research has shown that having a surgeon with bladder cancer expertise can improve the outcome of people with bladder cancer. Patients should talk with their doctor in detail to understand exactly what side effects may occur, including urinary and sexual side effects, and how they can be managed. In general, side effects may include:
Before surgery, talk with your surgeon about the possible side effects of the specific surgery you will have.
The types of systemic therapies used for bladder cancer include:
The medications used to treat cancer are continually being evaluated. Talking with your doctor is often the best way to learn about the medications prescribed for you, their purpose, and their potential side effects or interactions with other medications. It is also important to let your doctor know if you are taking any other prescription or over-the-counter medications or supplements. Herbs, supplements, and other drugs can interact with cancer medications. Learn more about your prescriptions by using searchable drug databases.
Chemotherapy is the use of drugs to destroy cancer cells, generally by keeping the cancer cells from growing, dividing, and making more cells. A chemotherapy regimen, or schedule, typically consists of a specific number of cycles given over a set period of time. A patient may get 1 medication at a time or a mix of various medications given at the same time.
There are 2 types of chemotherapy that might be used to treat bladder cancer. The type the doctor recommends and when it is given depends on the stage of cancer. Patients should talk with their doctor about chemotherapy before surgery.
Intravesical or local, chemotherapy is normally given by a Medical Oncologist. During this kind of treatment, drugs are delivered into the bladder through a catheter that has been inserted through the urethra. Local treatment only destroys superficial tumor cells that come in contact with the chemotherapy solution.
It can’t arrive at tumor cells in the bladder divider or tumor cells that have spread to different organs. Mitomycin-C (available as a generic drug), gemcitabine (Gemzar), and thiotepa (Tepadina) are the drugs used most often for intravesical chemotherapy. Other medications that are used include cisplatin (available as a generic drug), doxorubicin (available as a generic drug), and valrubicin (Valstar). In 2020, the FDA also approved mitomycin (Jelmyto) for the therapy of patients with poor quality upper tract urothelial cancer.
The most common regimens for systemic, or whole-body, chemotherapy to treat bladder cancer include:
Many foundational chemotherapies keep on being tried in clinical trials to help discover which medications or combinations of medications work best to treat bladder cancer. Generally a combination of medications works in a way that is better than 1 medication alone. Researchers are also studying when it is best to use chemotherapy, either before or after surgery.
If platinum chemotherapy recoils or eases back cutting edge or metastatic bladder Cancer, immunotherapy with avelumab (Tecentriq, see underneath) might be used to attempt to forestall or defer the Cancer from returning and to assist people with living longer. This is called switch maintenance treatment.
Side effects of chemotherapy depend on the individual and the dose used, but they can include fatigue, risk of infection, nausea and vomiting, hair loss, loss of appetite, and diarrhea. These side effects usually go away after treatment is finished.
Immunotherapy also called biologic treatment, is designed to support the body’s natural defenses to fight cancer. It uses materials made either by the body or in a laboratory to improve, target, or restore immune system function. It can be given locally or throughout the body.
Bacillus Calmette-Guerin (BCG). The standard immunotherapy drug for bladder cancer is a weakened bacterium called BCG, which is similar to the bacteria that cause tuberculosis. BCG is placed directly into the bladder through a catheter. This is called intravesical therapy. BCG attaches to the inside lining of the bladder and stimulates the immune system to destroy the tumor. BCG can cause flu-like symptoms, chills, mild fever, fatigue, a burning sensation in the bladder, and bleeding from the bladder.
Bacillus Calmette-Guerin (BCG). The standard immunotherapy drug for bladder disease is a debilitated bacterium called BCG, which is like the microscopic organisms that cause tuberculosis. BCG is set legitimately into the bladder through a catheter. This is called intravesical treatment. BCG joins within the covering of the bladder and animates the invulnerable framework to pulverize the tumor. BCG can cause influenza-like side effects, chills, mellow fever, weariness, a consuming sensation in the bladder, and seeping from the bladder.
Interferon (Roferon-A, Intron A, Alferon). Interferon is another kind of immunotherapy that can be given as intravesical therapy. It is now and then joined with BCG if utilizing BCG alone doesn’t help treat Bladder Cancer.
Targeted therapy is a therapy that objectives the cancer’s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. This kind of therapy blocks the development and spread of cancer cells while restricting harm to healthy cells.
Not all tumors have similar targets. To find the high-quality treatment, your doctor may run tests to identify the genes, proteins, and other factors in your tumor. This helps doctors better match each patient with the high-quality treatment whenever possible. In addition, research studies keep on discovering more about specific molecular targets and new medicines coordinated with them.
Targeted therapy for bladder cancer includes erdafitinib (Balversa). Erdafitinib is a drug given by mouth (orally) that is approved to treat people with locally advanced or metastatic urothelial carcinoma with FGFR3 or FGFR2 genetic mutations that has continued to grow or spread during or after platinum chemotherapy. There is a specific FDA-approved companion test to find out who may benefit most from treatment with erdafitinib.
Talk with your doctor about possible side effects of a specific medication and how they can be managed.
Radiation therapy is the use of high-energy x-rays or different particles to destroy cancer cells. A doctor who specializes in giving radiation therapy to treat cancer is called a radiation oncologist. The most well-known kind of radiation therapy is called external-beam radiation therapy, which is radiation therapy given from a machine outside the body. When radiation therapy is given by implants, it is called internal radiation therapy or brachytherapy. However, brachytherapy is not commonly used in
bladder cancer. A radiation therapy regimen, or schedule, generally consists of a specific number of treatments given over a set period of time.
Radiation therapy is typically not used by itself as a primary treatment for bladder cancer, but however, it might be given in combination with chemotherapy. Some people who can’t get chemotherapy may get radiation treatment alone. Combined radiation therapy and chemotherapy might be used to treat cancer that is founded only in the bladder:
Side effects from radiation therapy may include fatigue, mild skin reactions, and loose bowel movements. For bladder cancer, side effects most commonly occur in the pelvic or abdominal area and may include bladder irritation, the need to pass urine frequently during the treatment period, and bleeding from the bladder or rectum. Most side effects go away soon after treatment is finished.
A: The general 5-year survival rate for people with bladder cancer is 77%. The overall 10-year survival rate is 70% and the overall 15-year survival rate is 65%. However, survival rates depend on many factors, including the type and stage of bladder cancer that is diagnosed.
A: Bladder cancer generally affects older persons. However, some people are at more risk such as white people, smokers, and mostly men who are older than 60 years. Also, the people who work at leather and rubber industries are at more risk. Some people who are exposed to chemicals through their profession such as painters, hairdressers and machinists will also be at risk.
A: Common signs are pain while urinating, blood in urine, and urgency in urination, need to urinate very often. Sometimes the signs are often confused with other related problems but if symptoms are persistent one must see a doctor for further diagnosis.
A: Pain during urination and blood in urine may be signs of bladder cancer. However the same symptoms are also possible for kidney cancer or may be some other less serious issue such as kidney stones. However blood in urine is an immediate condition to visit the doctor immediately.
A: Bladder Cancer usually grows very slow and confined mostly to the bladder in the initial stages.When the cancer spreads it may travel to adjacent lymph nodes or invade the nearby organs sometimes it may also spread to lungs, liver and bones.
A: Bladder cancer treatment depends on the stage of the cancer. The prognosis depends on the age of the patient and other health conditions. The common procedures will be the surgery to remove the bladder, chemotherapy, radiation, immunotherapy and sometimes the combination of all these treatments. If the bladder is removed then a reconstructive surgery will be made to create a new path for urine storage.
A: The researchers are always looking for new and better ways to treat bladder cancer such as targeted immune therapies and testing new drugs in the clinical trials. If the patient has agreed to participate in clinical trials certain new drugs and new treatment approaches will be administered.
A: The side effects after the bladder cancer treatment will depend on the stage of cancer treated. Nausea, weight loss, hair loss and feeling of weakness are the common side effects after cancer therapy. The risks will increase with age of the patients. However, the complications will reduce with time if treatment is taken immediately.
A: Chronic irritation to the bladder such as urinary tract infections, smoking, medications used for diabetes, exposure to chemicals at the workplace and exposures to radiation are the main causes. It may also be hereditary to some extent.
A: Yes. It is possible and most of the patients do. If the bladder is removed totally the surgeon will create another pathway to eliminate urine.