The starting cost of Sickle cell anemia treatment in India is 15,000 USD. The price of sickle cell anaemia treatment is not fixed, but it varies as per the causes, symptoms and other health conditions in the patient.
However, if you compare the cost of the treatment to other countries, you will realize that the expenses in India are very less. To be specific, it is almost one-fourth of the total amount of treatment in the US.
Sickle cell anemia is a sickle cell disease. This is an inherited red blood cell disorder where the red blood cells in the body are not healthy enough to carry oxygen throughout the body. The normal red blood cells are round in shape and hence can easily move through the blood vessels. The abnormal once are sickle-shaped or of the shape of a crescent moon; hence the name of the disease. This particular shape makes the locomotion of the blood cells difficult within the rounded blood vessels. Hence the oxygen-carrying capacity of the blood drastically reduces.
This disease is an inherited one— the parents of the patient having the disease pass on the mutated gene to the cells. But the parents need not necessarily show any signs or symptoms of the disease as it is recessive in their bodies but is active in the body of their ward.
The sickle cell anemia patient has an abnormality in the protein, hemoglobin, in the red blood cell, which is responsible for carrying oxygen throughout the body. The people who have this disease inherit two abnormal hemoglobin genes from each of their parents. This hemoglobin is called S or sickle hemoglobin. Depending upon this, sickle cell disease can be classified into the following types:
In all the above types of sickle cell diseases at least one of the two abnormal cells causes the body to make the hemoglobin S. But when both the inherited genes are mutated the cell has hemoglobin SS, this disease is called sickle cell anemia. It is one of the most common sickle cell diseases. Other common diseases are Haemoglobin SC and Haemoglobin SB. The diseases Haemoglobin SD and Haemoglobin SE are rare and not very common.
Sickle cell anemia is a genetic blood disorder that can cause a wide range of symptoms and complications. Common symptoms of sickle cell anemia include:
It’s important to note that the severity and frequency of these symptoms can vary from person to person. Additionally, individuals with sickle cell anemia may go through periods of relative health and well-being between episodes of symptoms and complications.
Treatment and management of sickle cell anemia focus on alleviating symptoms, preventing complications, and improving the overall quality of life for individuals with the disease. This often involves medications, blood transfusions, and other supportive measures. Regular medical follow-up and care are essential for those with sickle cell anemia.
The diagnosis of sickle cell anemia typically involves a combination of clinical evaluation, laboratory tests, and genetic testing. Here are the key steps involved in diagnosing sickle cell anemia:
1. Clinical Evaluation:
2. Blood Tests:
Blood tests are a crucial part of the diagnostic process. The following blood tests are commonly used to diagnose sickle cell anemia:
3. Peripheral Blood Smear:
4. Genetic Testing:
5. Family History:
6. Additional Tests:
Once a diagnosis of sickle cell anemia is confirmed, the healthcare provider will work with the patient to develop an appropriate treatment plan and provide education about the condition. Regular monitoring and follow-up care are essential to manage the disease and prevent complications.
It’s important to note that sickle cell anemia can be diagnosed in newborns through newborn screening programs in many countries. Early diagnosis allows for prompt intervention and management, which can improve outcomes for individuals with the condition.
1. Blood Transfusion: Blood transfusions are commonly used to prevent and treat complications, such as stroke, in individuals with sickle cell disease. During a transfusion, donated blood is given through a vein to increase the number of normal red blood cells and reduce symptoms.
However, there are potential risks associated with transfusions, including an immune response to the donor blood, difficulty finding future donors, and the risk of infection. Additionally, excess iron buildup in the body can occur, potentially leading to damage of organs such as the heart and liver. In some cases, treatment may be needed to reduce iron levels in those who receive regular transfusions.
2. Stem Cell Transplantation: stem cell transplant, also known as a bone marrow transplant, which involves replacing the affected bone marrow with healthy bone marrow from a matched donor, typically a sibling without sickle cell anemia. This procedure is typically recommended only for individuals, usually children, with significant symptoms and complications of sickle cell anemia.
It’s important to discuss treatment options with a healthcare provider who specializes in sickle cell disease to determine the best course of action for an individual’s unique needs.
1. What is sickle cell anemia?
2. How is sickle cell anemia inherited?
3. What are the common symptoms of sickle cell anemia?
4. How is sickle cell anemia diagnosed?
5. Is there a cure for sickle cell anemia?
6. What are the treatment options for sickle cell anemia?
7. Can sickle cell anemia be prevented?
8. What is the life expectancy for someone with sickle cell anemia?
9. Are there specific dietary recommendations for people with sickle cell anemia?
10. Can people with sickle cell anemia have children?